The principles of providing emergency care for patients with pancreatic necrosis

Abstract

At the present stage, the treatment of patients with pancreatic necrosis is one of the most urgent surgical tasks. Pancreatic necrosis is a destructive lesion of the pancreas, often leading to the development of multiple organ failure. The pathogenesis is based on a violation of the mechanism of counteraction to proteolytic enzymes produced by the pancreas. Pancreatic necrosis is a formidable complication of pancreatitis, with mortality ranging from 30 to 70 %. Today, in terms of the frequency of occurrence in surgical practice, this pathology ranks second after acute appendicitis. The leading role in the prevention of the development of pancreatic necrosis and the prevention of mortality is taken by early detection, timely hospitalization and the fastest possible start of therapeutic measures. A special place in the treatment of pancreatic necrosis is occupied by measures aimed at rehydration, optimization of hemodynamic parameters, the prescription of vasoactive drugs and prophylactic antibiotics in order to prevent the development of infectious complications.