The primary structure of the mitochondrial genome of Saccharomyces cerevisiae — a review

Abstract

We have collated and compiled all the available primary structure data on the mitochondrial genome of Saccharomyces cerevisiae. Data concern 78 500 bp, namely 92% of the “long” genomes; they are derived from several laboratory strains. Interstrain differences belong to three classes: (i) a small number of large deletions/additions, mainly concerning introns; (ii) a large number of small (10–150 bp) deletions/additions located in the intergenic sequences; (iii) 1–3 bp deletions/additions and point mutations; the interstrain sequence divergence due to the latter, is of the order of 2% for the strains compared; this low value is, however, an overestimate because of sequence mistakes.