The preventive effect of glass ionomer restorations on new caries formation: A systematic review and meta-analysis

Abstract

ObjectiveTo investigate the effectiveness of glass ionomer cement (GIC) restorations on preventing new caries in primary or permanent dentitions compared with other types of restorations. DataRandomized controlled clinical trials evaluating caries experience increment or caries incidence in patients with GIC restorations, including conventional GIC (CGIC) and resin-modified GIC (RMGIC) restorations, were included. SourcesA systematic search of publications in English was conducted in PubMed/Medline, Web of Science, Cochrane, and Scopus databases. Study selection/resultsThis review included 10 studies reporting caries preventive effect of GIC restorations and selected 5 studies for meta-analysis. Patients with GIC restorations showed lower caries incidence compared with other restorations in primary and permanent dentition [RR=0.67, 95% CI:0.55–0.82, p < 0.0001]. Patients with CGIC restorations showed lower caries incidence compared with amalgam restorations [RR=0.57, 95% CI:0.43–0.76, p = 0.0001] and RMGIC restorations [RR=0.70, 95% CI:0.56–0.87, p = 0.002], but no statistical difference with composite resin restorations [RR=0.73, 95% CI:0.51–1.04, p = 0.08] in primary dentition. Patients with RMGIC restorations showed no statistical differences of caries incidence compared with composite resin restorations in primary and permanent dentition [RR=0.83, 95% CI:0.56–1.22, p = 0.33]. ConclusionsGIC restorations presented a better preventive effect on new caries than other restorations did in primary and permanent dentitions. CGIC restorations presented a better caries preventive effect on new caries than RMGIC and amalgam restorations in primary dentitions did. RMGIC restorations showed similar preventing effect on new caries with composite resin restorations in primary and permanent dentitions. Clinical significanceThis review affirmed the potential of GIC in preventing new caries development in the dentition.