Abstract

The use of the serum of immunized goats as a means of preventing measles is comparatively new. Hoyne and Gasul 1 recently reported a series of cases in which goat serum was used for this purpose, and they showed that 88 per cent of their patients were protected against measles, the remaining 12 per cent developing mild attacks of the disease. Other methods of immunization against measles have been used. Nicolle and Conseil 2 and Richardson and Connor 3 used convalescent human measles serum as early as 1918. Rietschel 4 used convalescent human measles serum as early as 1918. Herrman 5 attempted to obtain active immunization by swabbing the mucous membranes of the nostrils of contacts with diluted secretions from patients with measles. All these methods, however, have definite disadvantages. Convalescent human serum is not usually obtainable in sufficient quantity when most desired, as in epidemics. Haas and Blum 6

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