The prevalence ofmetabolic syndrome and lifestyle in bipolar disorder patients

Abstract

：Objective To explore theprevalence of metabolic syndrome( MetS) and its components in patients with bipolardisorder and their lifestyle. Methods Collected 148 cases of bipolar disorder in patientswith body mass index (BMI),blood glucose,blood pressure,triglyceride(TG),high-densitylipoprotein( HDL-C) etc, and self-compiled scale was used to assess their lifestyle. Allpatients were followed 6 months. The patients werecompared with 65 normal controls.Results The patients group in the baseline period,treatment after 1 months,3 months and 6months,the incidence of MetS was as followed:11.5% ,15.5% ,18.2% ,20.9%. The patients atall stages,the incidence of MetS,BMI≥25kg/m2 ,high TG levels,low HDL-C levels and hypertensionwere significantly higher than the control (P<0.01). After 6 months of treatment theincidence of MetS,hypertriglyceridemia were higher than baseline (P < 0.05). Thepatients group' s work intensity, frequency of exercise, eat more than 3 times per daycompared with the control group were significantly different (P<0.01, P<0.05).Conclusion The incidence of MetS and hyperuricemia in patients with bipolar disorder aftertreatment is higher than the control group; as a continuation of the treatment,theincidence of metabolic abnormalities increased gradually. Unhealthy lifestyle, lack ofexercise,unreasonable diet maybe increase the risk of metabolic disorders. Key words: Bipolardisorder; Metabolic syndrome; Lifestyle