Abstract

Objectives: Temporomandibular joint (TMJ) involvement in rheumatoid arthritis (RA) patients has been described in the literature; however, its incidence varies greatly. In this study, we aimed to determine the prevalence and clinical characteristics of TMJ involvement in RA patients.Materials and Methods: The present study consisted of 60 individuals with RA. The patients were assigned to two groups, based on TMJ involvement: patients with TMJ involvement and patients without TMJ involvement. We defined TMJ involvement based on the findings of the questionnaires and clinical examination by a rheumatologist. The symptoms and signs were recorded by a single trained dentist.Results: The majority of the participants were women (n=49, 81.66%), with the mean age of 43.9±15.52 years (range: 21-78 years). Thirty-five patients (58.3%) had clinical evidence of TMJ involvement. The levels of C-reactive protein (CRP) and rheumatoid factor (RF) were found to be correlated with TMJ involvement. There was no significant correlation between TMJ involvement and erythrocyte sedimentation rate (ESR), age, gender, treatment duration, and disease duration.Conclusion: The high level of CRP in RA patients with TMJ involvement was reported. TMJ pain was reported in almost half of the patients. There was also a significant correlation between TMJ involvement and RF.

Highlights

  • Rheumatoid arthritis (RA) is a systemic disease characterized by chronic inflammation, joint swelling, joint tenderness, and destruction of synovial joints [1]

  • A total of 60 RA patients were analyzed in this study

  • The present study investigated laboratory indicators of RA (CRP, erythrocyte sedimentation rate (ESR), and rheumatoid factor (RF)), which might be related to the involvement of temporomandibular joint (TMJ)

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Summary

Introduction

Rheumatoid arthritis (RA) is a systemic disease characterized by chronic inflammation, joint swelling, joint tenderness, and destruction of synovial joints [1]. The prevalence of RA is 0.5-1% in the general population, and it is more frequent in women. RA is recognized as the most common inflammatory joint disorder [2]. It usually affects multiple joints of the body, often starting in the peripheral joints [1, 2]. The temporomandibular joint (TMJ) is rarely the first joint to be affected [3]. The frequency of clinical TMJ involvement ranges from 5% to 86%, with bilateral involvement reported as the most frequent [4, 5]

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