Abstract

Cancer is one of the most prevalent causes of mortality worldwide. In the cervix, it is confirmed to be caused by different high-risk human papillomavirus (HPV) types. Although many studies have already been conducted worldwide on the epidemiology of HPV infection and their oncogenic properties, limited data are available on HPV prevalence, incidence and its impacts in Egypt.

Highlights

  • License (CC BY 4.0).http://creativecommons.org/licenses/by/4.0/ Human papillomavirus infection (HPV infection) is an infection caused by a Open AccessDNA virus from the Papillomaviridae family with more than 170 subtypes which have been described and it is well known as the most common viral sexually transmitted infection (STI) worldwide [1]

  • Egyptian women using the new liquid based cytology technique and our results provide important information for public health authorities considering human papillomavirus (HPV) prevention in Egypt

  • Among 1000 women underwent the Liquid Based Cytology (LBC) test, 143 women were positive to HPV DNA findings (14.3%), while the rest of women 857 were test free (85.7%) (Diagram 1)

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Summary

Introduction

Http://creativecommons.org/licenses/by/4.0/ Human papillomavirus infection (HPV infection) is an infection caused by a Open Access. DNA virus from the Papillomaviridae family with more than 170 subtypes which have been described and it is well known as the most common viral sexually transmitted infection (STI) worldwide [1]. About 90% of HPV infections cause no symptoms and resolve spontaneously within two years. In some cases, an HPV infection persists and results in either warts or precancerous lesions [2]. These lesions, depending on the site affected, increase the risk of cancer of the cervix, vulva, vagina, penis, anus, mouth, or throat [3]. Most cervical cancer is due to HPV; two strains, HPV16 and HPV18, account for 70% of cases.

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