Abstract
Background Asthma is an important reason for hospitalization in children aged under five years. Information about the current status of asthma in Iranian children can help the Iranian health sector plan carefully and prevent asthma incidence by educating the families. The present systematic review and meta-analysis is aimed at estimating asthma prevalence in Iranian children and adolescents. Method Data were found using keywords such as prevalence, epidemiology, asthma, adolescent, children, pediatrics, Iran in Web of Science, Scopus, PubMed, Cochrane, and Embase databases. Three national databases, including Magiran, Barakat Pharmed Co (Iran medex), and Scientific Information Databank (SID) were searched until 1 October 2020. Cross-sectional and original studies were included in the study, and then, quality assessment was done using the National Institutes of Health's Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies. A pooled estimated prevalence of asthma was calculated using Der Simonian-Laird random model. Egger's test was used to evaluate publication bias. The data were analyzed using the STATA software version 16. Results 30 studies were selected and investigated. The prevalence of asthma in children and adolescents was 6% and 8%, and the prevalence in boys and girls was 9% and 8%, respectively. Among the asthma symptoms, wheezing had the most prevalence (17% in children and 19% in adolescents) and sleep disturbance had the lowest prevalence (6% in children and 6% in adolescents). Conclusion The prevalence of asthma in Iranian children and adolescents is lower than in the world. Existing strategies should be pursued followed. Also, guidelines for asthma control and prevention should be considered in the future.
Highlights
Asthma is an important reason for hospitalization in children aged under five years
The present study was performed based on Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) instruction [8] to examine asthma prevalence among children and adolescents in Iran
1270 articles were found; by reviewing the articles, 1090 duplicate and irrelevant articles with inadequate data and other exclusion factors were removed and 30 articles were selected for this systematic review study (Figure 1)
Summary
Asthma is an important reason for hospitalization in children aged under five years. Information about the current status of asthma in Iranian children can help the Iranian health sector plan carefully and prevent asthma incidence by educating the families. The present systematic review and meta-analysis is aimed at estimating asthma prevalence in Iranian children and adolescents. Data were found using keywords such as prevalence, epidemiology, asthma, adolescent, children, pediatrics, Iran in Web of Science, Scopus, PubMed, Cochrane, and Embase databases. The prevalence of asthma in Iranian children and adolescents is lower than in the world. Asthma is one of the leading chronic respiratory diseases in children in the world. This disease is one of the main reasons for hospitalizations of children under five years old and has been increasing in recent years [1]. Records identified through database searching [Google scholar, pubmed, scopus, web of science, cochrane, and science direct] (n = 1270) Identification Screening.
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