Abstract
ObjectivesThis study aimed to examine the prevalence and risk factors of dyslipidemia in different diabetic progression stages among middle-aged and elderly Chinese populations.MethodsThe 2010–2012 China National Nutrition and Health Survey (CNNHS) is a nationally representative cross-sectional study. In the present study, a total of 69,974 participants aged ≥ 45 years were included. Dyslipidemia was defined based on the Chinese adult dyslipidemia prevention guide. A multivariable logistic regression model was performed to examine the associations between risk factors and dyslipidemia.ResultsThe prevalence of dyslipidemia was 39.9%, 46.8%, and 59.3% in participants with normal glucose, prediabetes, and type 2 diabetes mellitus (T2DM). Women had a lower dyslipidemia prevalence than men (38.7% vs. 43.3%). Dyslipidemia prevalence was positively associated with the education level and inversely correlated with the physical activity level, and negatively related to age only among prediabetes and T2DM groups (P for trend < 0.05). Obesity, abdominal obesity, and hypertension were associated with dyslipidemia.ConclusionsThe prevalence of dyslipidemia was relatively high among middle-aged and elderly T2DM person. There are different associations between multiple risk factors and dyslipidemia in different diabetic progression stages.
Highlights
The prevalence of type 2 diabetes mellitus (T2DM) has increased dramatically worldwide
Dyslipidemia prevalence was positively associated with the education level and inversely correlated with the physical activity level, and negatively related to age only among prediabetes and T2DM groups (P for trend < 0.05)
We aimed to investigate dyslipidemia prevalence and associated factors in different diabetic progression stages among middle-aged and elderly populations based on the data of the 2010–2012 China National Nutrition and Health Survey
Summary
The prevalence of type 2 diabetes mellitus (T2DM) has increased dramatically worldwide. According to the China Chronic Disease and Risk Factors Surveillance study, the estimated overall prevalence of diabetes and prediabetes was 10.9% and 35.7% among adults, respectively [1]. Individuals with T2DM had two-to-four fold increase in cardiovascular disease (CVD) risk [2]. Subjects with T2DM had an increased risk of cardiovascular mortality [3]. According to the China National Survey of Chronic Kidney Disease study, the prevalence of dyslipidemia was 34.0% among adults aged 18 years in 2010 [5]. A multicenter survey showed that the prevalence of dyslipidemia was 67.1% among T2DM subjects aged 40 years [6]
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