The Prevalence and Causes of Primary Infertility in Iran: A Population-Based Study.

Hadigheh Kazemijaliseh,Farhad Hosseinpanah,Davood Khalili,Fereidoun Azizi,Fahimeh Ramezani Tehrani,Samira Behboudi-Gandevani

doi:10.5539/gjhs.v7n6p226

Hadigheh Kazemijaliseh, Farhad Hosseinpanah + Show 4 more

Open Access

https://doi.org/10.5539/gjhs.v7n6p226

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Abstract

Background:Primary infertility is a health issue among women over the world. The aim of this study was to investigate the prevalence and causes of primary infertility based on a population-based study in an urban area of Iran.Materials and Methods:In a cross-sectional study, a total of 1067 married women who participated in the Tehran Lipid and Glucose Study were randomly selected using systematic random sampling. Unmarried women, those with unwilling pregnancy and duration of marriage below one year were excluded from the study. Data was collected by using validated ad-hoc questionnaires. Descriptive and inferential statistics were used for data analysis.Results:The mean (SD) of age and marriage age of the studied women were 40.3 (9.3) and 20.6 (4.49) years, respectively; the overall prevalence of lifetime primary infertility among couples was 17.3% (185/1067). Ovulatory disorder (39.7%) and male factors (29.1%) were the main causes of primary infertility. In addition, 31 (17%) of the women were diagnosed with more than one cause. According to the logistic regression analysis, primary infertility was independently related to the old age of women (OR: 1.37; 95% CI: 1.14–13.63, P.value: 0.001), higher BMI (OR: 1.95; 95% CI: 1.87–4.14, P.value: 0.003), active smoking (OR: 1.47; 95% CI: 1.38–3.53, P.value: 0.012) and higher educational level (OR: 2.23; 95% CI: 1.12–5.53, P.value: 0.03).Conclusion:The prevalence of primary infertility in Iran was higher than the worldwide trends of infertility, indicating that understanding such risks help healthcare providers and policy makers to design and implement interventions to slow down this trend.

Highlights

Infertility is a common problem affecting one couple out of every six couples (Brugo-Olmedo, Chillik, & Kopelman, 2001)
According to the logistic regression analysis, primary infertility was independently related to the old age of women (OR: 1.37; 95% CI: 1.14–13.63, P.value: 0.001), higher BMI (OR: 1.95; 95% CI: 1.87–4.14, P.value: 0.003), active smoking (OR: 1.47; 95% CI: 1.38–3.53, P.value: 0.012) and higher educational level (OR: 2.23; 95% CI: 1.12–5.53, P.value: 0.03)
The prevalence of primary infertility in Iran was higher than the worldwide trends of infertility, indicating that understanding such risks help healthcare providers and policy makers to design and implement interventions to slow down this trend

Summary

Introduction

Infertility is a common problem affecting one couple out of every six couples (Brugo-Olmedo, Chillik, & Kopelman, 2001). It is defined as incapacity to become pregnant after mostly 12 months of sexual intercourse, without using any contraception. In this respect, primary infertility was defined as the “Inability to conceive within one year of exposure to pregnancy (i.e.-being sexually active, usingnon-contraception, and non-lactating) among women aged 15-49 years” (Nygren et al, 2011). The prevalence of infertility has been significantly increased (Brugo-Olmed et al, 2001). The increasing trend could be due to delayed childbearing of couples, alterations in semen quality due to habits such as cigarette smoking and alcohol, changes in sexual behavior and elimination of most taboos (Brugo-Olmed et al, 2001). Primary infertility is a health issue among women over the world.

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