The Present Situation and Prospection for Gene Therapy of Breast Cancer

Abstract

Breast cancer is characterized by a series of genetic mutations and is therefore ideally placed for gene therapy intervention. The aim of gene therapy is to deliver a nucleic acid-based drug to either correct or destroy the cells harboring the genetic aberration. To date, surgery, chemotherapy, radiotherapy and endocrine therapy have generated small improvements in clinical outcomes, but breast cancer is still able to recur and metastases. Thus, the exploration of more effective and safer therapeutic modalities is urgently needed. Gene therapy strategies may be beneficial for the successful treatment of carcinoma of the breast. The immediate future breast cancer gene therapy would suggest increasing success in using cancer gene therapy as adjunct therapy in local control of many cancers.In our study, we want to highlight these different gene therapy strategies for carcinoma of the breast. And along with the intensive study in the pathogenesis of breast cancer, it will gain more breakthrough, and providing a new approach for clinical treatment of breast cancer.