Abstract
T Gulen, H Hagglund, B Sander, B Dahlen, G Nilsson. Clin Exp Allergy. 2014;44(9):1179–1187 There is substantial overlap between the clinical manifestations of unexplained anaphylaxis (UEA) and clonal mast cell disorders (CMDs). The objective of the study was to examine the hypothesis that the pathogenesis of UEA reflects the presence of aberrant subpopulations of mast cells. Thirty (14 men, 16 women) patients (aged ≥18 years) referred to the Mastocytosis Centre at the Karolinska University Hospital for suspicion of a clonal mast cell disorder, with history of ≥1 episodes of UEA and without signs of cutaneous mastocytosis, were recruited for study. Initial retrospective data were collected through review of electronic records. UEA was diagnosed after …
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