Abstract

To evaluate the presence of anemia in patients with chronic lower limb ulcers based on profile and hematometric indices. This is a cross-sectional study carried out in a university hospital in Rio de Janeiro. The sample was composed of 64 participants with lower limb ulcers and evolution time greater than 12 weeks. Data was collected between May/2016 and December/2017 from hematological analyses, records from medical records, and wound assessment form. 36 (56.2%) were male; 38 (59.4%) between 60 and 80 years old; 56 (87.5%) with chronic diseases and 52 (81.2%) with venous ulcers. 6 years mean of active ulceration. Anemia was detected in 36 (56.2%), 27 (75%) of which were normochromic and normocytic; 14 (38.8%) had deficiency anemia recorded in their medical chart. The low hemoglobin concentration is recurrent among the participants characterizing an anemia condition, whose profile reveals congruence to the anemia of chronic disease.

Highlights

  • METHODSDifferent mechanisms can cause the anemic syndrome; among them, the ones characterized by disturbances in iron homeostasis stand out, as they cause deficient hemoglobin synthesis (Hb)(1)

  • Anemia resulting from iron deficiency is the most prevalent, the proportion varies according to the local conditions of the population examined[5,6]; this article discusses a type of anemia called anemia of chronic disease (ACD)

  • This study aims at assessing the presence of anemia in patients with chronic lower limb ulcers based on profile and hematometric indicators

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Summary

Introduction

Different mechanisms can cause the anemic syndrome; among them, the ones characterized by disturbances in iron homeostasis stand out, as they cause deficient hemoglobin synthesis (Hb)(1). In these cases, the hemoglobin concentration in the blood is usually below the limit advised as usual[2]. Typical Hb reference values for the definition of blood anemia vary according to the sex and age of the individual, considering the levels of this analyte in a group of individuals representative of a population[4]. Anemia resulting from iron deficiency is the most prevalent, the proportion varies according to the local conditions of the population examined[5,6]; this article discusses a type of anemia called anemia of chronic disease (ACD). A very common clinical syndrome, in which its total incidence is surpassed only by iron deficiency anemia, being more prevalent among elderly individuals[1,2,7]

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