Abstract

An ATPase stimulated by HCO 3 − -ions and inhibited by SCN-ions could be found in glandula submandibularis of rabbit with following properties: 1. It is stimulated by a variety of oxybases according to a general base catalytic mechanism. 2. It is inhibited by both SCN−-and OCN−-ions. 3. It can be solubilized by Triton X 100 hereby yielding a marked increase in the activity response to HCO 3 − -and SCN−-ions. 4. It can be distinguished from mitochondrial ATPase because of the different behaviour of this enzyme and mitochondrial marker such as succinic dehydrogenase using sucrose gradient centrifugations.

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