Abstract
This review summarizes relevant publications and our recent work related to the structure and the function of the lens epithelium and its role in the formation of cataract as well as its correlation with changes in intracellular calcium, as studied on different types of preparations. It is emphasized that the human lens capsule preparation isolated during the cataract surgery is an adequate source for the studies of lens epithelial cells and we highlight the possibilities for studying the intracellular calcium homeostasis and the cataract.
Highlights
Escherichia coli (E. coli) are normal inhabitants of the gastrointestinal tract of animals and human beings [1,2,3]
Outbreaks of E. coli O157 have been reported in different parts of the world and antibiotic use is controversial because of the potential to increase production and secretion of Shiga toxins
The overall prevalence of carcass contamination with E. coli species of the present study in the slaughtered animals was 30.97 % (n=113) which is higher than 4.4% (n=885) prevalence reported in Kenya [12]
Summary
Escherichia coli (E. coli) are normal inhabitants of the gastrointestinal tract (lower ileum and large intestine) of animals and human beings [1,2,3]. Infection with E. coli O157:H7 is a major food borne and zoonotic pathogen responsible for hemorrhagic colitis and hemolytic uremic syndromes in humans. Transmission to human occurs through consumption of undercooked meat, unpasteurized dairy products, and vegetables or water contaminated by feces of carrier animals [1]. Outbreaks of E. coli O157 have been reported in different parts of the world and antibiotic use is controversial because of the potential to increase production and secretion of Shiga toxins. Differentiation of pathogenic strains from the normal flora depends on the identification of virulence characteristics [4]
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