Abstract
The preparation of resin-bound nitroalkenes via a microwave assisted Knoevenagel reaction of resin-bound nitroacetic acid with aryl and alkyl substituted aldehydes is described. The potential of these resin-bound nitroalkenes for application in combinatorial chemistry is demonstrated by a Diels–Alder reaction with 2,3-dimethylbutadiene and one-pot three component tandem [4+2]/[3+2] reactions with ethyl vinyl ether and styrene. The cycloadditions were promoted by high pressure.
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