Abstract

Graphene oxide (GO) can be readily modified for particular applications due to the existence of abundant oxygen-containing functional groups. Graphene oxide-based materials (GOBMs), which are biocompatible and hydrophilic, have wide potential applications in biomedical engineering and biotechnology. In this review, the preparation and characterization of GO and its derivatives are discussed at first. Subsequently, the biocompatibility and tribological behavior of GOBMs are reviewed. Finally, the applications of GOBMs as lubricants in bio-tribological systems are discussed in detail.

Highlights

  • The study of graphene has been one of the most exciting topics in material science and many other research fields since the first report of the preparation and isolation of single graphene layers in2004 [1]

  • This review focuses on graphene oxide (GO) and GO-based materials (GOBMs), as well as their biocompatibility and tribological performance

  • Graphene oxide-based materials (GOBMs) are expected to have good tribological performances in appropriate systems, because they are regarded as derivatives of self-lubricating graphite, which has a layered structure and exhibits a low friction and wear rate when used as solid lubricants

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Summary

Introduction

One is how to produce graphene sheets at a sufficient scale. Graphite, despite that it is inexpensive and available in large quantities, does not readily exfoliate to yield monolayer graphene sheets. The other is that graphene sheets are hard to be incorporated and distributed homogeneously into various matrices for applications. Graphite oxide, containing abundant oxygen-based groups, can be obtained from the oxidation of graphite, but can be readily exfoliated to graphene oxide (GO) nanosheets using ultrasonic devices. This review focuses on GO and GO-based materials (GOBMs), as well as their biocompatibility and tribological performance. The preparation and characteristics of its derivatives are discussed. The biocompatibility and specific tribological behavior are reviewed. The possibilities to use GOBMs for bio-tribological applications, such as artificial joint replacement, is discussed in detail

Preparation of GO
Characterization of GO
Derivative of GO and Their Characteristics
Functionalized Derivatives of GO
GO-Based Thin Films
GO-Based Nanocomposites
Biological Property of GO-Based Materials
Tribological Behavior of GOBMs
Application of GOBMs in Bio-Tribological Systems
Conclusions and Prospect
Conflicts of Interest
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