Abstract
F -alkyl cadmium reagents can be readily prepared via the direct reaction of F -alkyl iodides with cadmium powder in DMF at room temperature. Similar reaction of bromopentafluorobenzene with cadmium powder in DMF at room temperature affords the F -aryl cadmium reagent in excellent yield. This approach provides a rapid, easily scaled up, one-pot procedure to these valuable synthetic reagents from commercially available precursors.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have