The Predictive Value of Trancranial Ultrasound Doppler Parameters for Intracerebral Hemorrhage in Preterm and Low Birth Weight Neonates

Abstract

Abstract Background Premature and low birth neonates are liable for many medical problems including intracranial hemorrhage. Transcranial Ultrasound examination and using different Doppler parameters of both ACA and MCA is considered as a good tool that is non invasive, cost effective and convenient to neonates to detect any intracerebral hemorrhage that they are risk for. Aim of the Work The aim of the current study was the assessment of the transcranial ultrasound as a predictive value of intracereberal hemorrhage in the examined neonates. Patients and Methods The study was performed on 33 preterm and low birth weight neonates attending Ain Shams University neonate intensive care unit and Ultrasound examination by B-Mode followed by Doppler examination were performed. Three neonates were died before performing the second examination. Examination was done at one day of birth considered as the first read and after 4-8 days which were considered as the second read to the rest 30 preterm neonates. Results Upon examination of 30 preterm and low birth neonates in two settings, they were categorized into hemorrhagic and non hemorrhagic groups. And by detecting the different Doppler parameters of both ACA and MCA in the two groups, it was found that the PSV2, MV, RI and PI gave a statistically significant difference between hemorrhagic and non hemorrhagic group. While ACA compared to MCA being has less branches and smaller diameter, its parameters are more sensitive in detection and prediction of hemorrhage than that of MCA. EDV1 of the ACA more than 8.1 cm/sec. was the most sensitive predictor of intracerebral hemorrhage in the present study. Conclusion In the current study, where more details examined upon ACA and MCA separately, it was found that EDV1 of the ACA has more predictive value than that of the EDV1 of MCA which is still can also used as a predictive value for intracranial hemorrhage.