Abstract
Objective To evaluate the value of clinical pulmonary infection score (CPIS) and acute physiology and chronic health evaluation Ⅱ (APACHEⅡ) in predicting the efficacy of noninvasive ventilation therapy in patients with acute exacerbations of chronic obstructive pulmonary disease(AECOPD). Methods The clinical data of 67 AECOPD patients with respiratory failure were analyzed with CPIS and APACHE Ⅱ were calculated respectively. The trachea cannula and death rates of patients with different CPIS and APACHE Ⅱ were observed. Results CPIS≥18 scores and APACHE Ⅱ≥25 scores indicated higher trachea cannula and death rates (P< 0.01).The area under the curve was above 0.90 in both CPIS and APACHE Ⅱ . Conclusions CPIS and APACHE Ⅱ can be helpful in giving timely trachea eannula to AECOPD patients with respiratory failure. CPIS and APACHE Ⅱ play important roles in evaluation and forecasting prognosis. Key words: Continuous positive airway pressure; Pulmonary disease,chronic obstructive; Respiratory insufficiency; Acute physiology and chronic health evaluation; Clinical pulmonary infection score
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