Abstract
Intraoperative lavage is a common practice that has been widely performed since its first description in the 1900s [1]. The intent is to dilute and remove debris, bacteria, tumor cells, and so forth from the operative cavity. Furthermore, peritoneal lavage with distilled water has been described after abdominal surgery for various cancers, with the hypothesis that the hypotonic shock conferred to potential free cancer cells may result in cell lysis and prevention of peritoneal seeding [2–5]. However, to date, there have been few data that describe the specific mechanism by which this occurs, or whether it results in efficacious cytocidal activity at all.
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