Abstract
Extended life expectancy and a desire to look younger demands that anti-aging research continue the search for the proverbial fountain of youth. Natural ingredients have long been a focal point in this research niche, with current science looking for means to improve phytochemical efficacy. This comes after the realization that phytochemicals may require biological activation before they are able to exert their efficacy. Microbial fermentation is an increasingly popular tool to avert these challenges and produce high quality natural actives with enhanced efficacy, along with any other potential effect offered, when using probiotic microorganisms. An example is the fermentation of Paeonia suffruticosa with Bifidobacterium bifidum which significantly improved tyrosinase inhibition and the antioxidant capacity of the extract. In addition to the therapeutic benefit, microbial fermentation is an economic and environmentally friendly option which is relatively simple to carry out. Although promising, literature clearly indicates the need for careful consideration in the selection of ideal conditions, methods, microbial strains and natural substrates to ensure success in the form of enhanced biological activity.
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