Abstract
Bacteria can produce new progeny in only 20 minutes (500,000 times faster than humans), enabling them to rapidly mutate and evolve ingenious methods to outwit just about all of the currently available antibiotics. These mechanisms can then disseminate rapidly through bacterial populations via transmissible pieces of DNA such as transposons, integrons and plasmids. This leads to resistance mechanisms becoming geographically dispersed and has resulted in the overall decrease in the susceptibility of microorganisms to antibiotics that used to be highly efficacious. There is an obvious need for new antibiotics that kill bacteria via novel mechanisms not previously exploited by existing agents; this will provide new generations of antibiotics unlikely to be compromised by preexisting resistance mechanisms. The fatty acid biosynthetic pathway is an essential metabolic process in bacteria and presents several novel targets for antibiotic development.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
