Abstract

Orodental problems have long been managed using herbal medicine. The development of nanoparticle formulations with herbal medicine has now become a breakthrough in dentistry because the synthesis of biogenic metal nanoparticles (MNPs) using plant extracts can address the drawbacks of herbal treatments. Green production of MNPs such as Ag, Au, and Fe nanoparticles enhanced by plant extracts has been proven to be beneficial in managing numerous orodental disorders, even outperforming traditional materials. Nanostructures are utilized in dental advances and diagnostics. Oral disease prevention medicines, prostheses, and tooth implantation all employ nanoparticles. Nanomaterials can also deliver oral fluid or pharmaceuticals, treating oral cancers and providing a high level of oral healthcare. These are also found in toothpaste, mouthwash, and other dental care products. However, there is a lack of understanding about the safety of nanomaterials, necessitating additional study. Many problems, including medication resistance, might be addressed using nanoparticles produced by green synthesis. This study reviews the green synthesis of MNPs applied in dentistry in recent studies (2010–2021).

Highlights

  • Nanotechnology is a field of science that deals with nanometer-sized objects, which are referred to as nanoparticles (NPs)

  • Zhao et al used silver nitrate immersion and UV radiation to insert agents in the manufacture of silver nanoparticles (AgNPs) into titania nanotubes (TiO2-NTs) on Ti implants. e antibacterial action against S. aureus was tested, and the findings showed that planktonic germs were inhibited over the first days

  • Sun et al revealed that acid-functionalized TiO2 NPs might be incorporated into dental resins that can be used as dental adhesives on human teeth. e reactive oxygen species (ROS) produced by these NPs when exposed to visible light can be used to boost the degree of vinyl conversion in resins, resulting in adhesives with improved shear bond strength to human teeth. e genotoxicity of the NPs and their potential for release from dental composites were investigated, and the results showed that there was a low danger of genotoxic effects [132]

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Summary

Introduction

Nanotechnology is a field of science that deals with nanometer-sized objects, which are referred to as nanoparticles (NPs). Nanobiotechnology is a unique method that has inspired the development of a variety of nanobiomaterials with applications in biology and medicine [6]. E broad application of medical nanosystems in different branches of dentistry, including prognosis, prevention, tissue regeneration, repair, and care, has been documented in numerous studies (Figure 1). Advancements in oral medicine nanosystems for individual prophylaxis are critical Due to their broad-spectrum antibacterial capabilities, metal nanoparticles (MNPs) have been used in various dental applications. Controlling oral biofilm production is a difficult challenge, but nanotherapeutics has been employed successfully in recent years by adding nanoparticles into a variety of dental materials [7]. The dental application of green synthesis (GS) in the production of MNPs has been reviewed in recent studies (2010–2021)

Metal Nanoparticles
Metal Nanoparticles’ Characterization
Metal Nanoparticle Antibacterial Mechanisms
Disadvantages of the Application of Metal Nanoparticles
Chemical Approach
Green Approach
Benefits of Plant-Delivered Green
Silver Nanoparticles
Objective
Gold Nanoparticles
Periodontal Disease
Stem Cell Technology
Dental Materials
Diagnostic Imaging
Iron Nanoparticles
Applications in Dentistry
Zinc Oxide Nanoparticles
Copper Nanoparticles
10. Future Prospects
11. Conclusion

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