Abstract
The bark of Syzygium cumini is potential as an antimicrobial agent, so this bark is a reservoir of endophytic fungi. The purpose of this study was to isolate endophytic fungi and determine its antifungal activity. Several methods used in this research are surface sterilization, endophytic isolation on plain media and media containing host plant, morphology identification of endophytic fungi and determine antifungal activity. Thirteen endophytic fungi have been isolated from the bark of S. cumini, in which seven and six endophytic fungi grow on the plain media and media containing host plants, respectively. Based on the morphology identification, these endophytic fungi include the genus Phomopsis, Colletotrichum and Aspergillus. Seven endophytic fungi displayed antifungal activity against pathogenic microorganisms. The results demonstrated that endophytic fungi isolate from S. cumini bark could be a source of antifungal agents.
Highlights
The frequency of infectious diseases, especially caused by pathogenic fungi has increased worldwide.a serious global concern is the overuse of antibiotics, so that pathogen microorganisms become resistant to the drug [1]
Thirteen endophytic fungi isolates have been isolated from the barks of S. cumini (L.) Skeels and they can be cultured on artificial media
Seven endophytic fungi isolates can grow on potato dextrose agar (PDA) medium, while six endophytic fungi isolates can grow on PDA containing host plant
Summary
The frequency of infectious diseases, especially caused by pathogenic fungi has increased worldwide. A serious global concern is the overuse of antibiotics, so that pathogen microorganisms become resistant to the drug [1]. The search for new antibiotics, especially antifungal agents still needs to be done. Many sources of bioactive compounds are found in nature, but currently, many researchers devote attention to microorganisms, such as endophytes, especially endophytic fungi. Endophytic microorganisms reside in tissues of living plants without causing any negative effect on its host plant [2]. Every plant is host to one or more endophytic microorganisms, which they able to produce secondary metabolites. Compounds produced by endophytes can be the same or different from its host [3]
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