Abstract
1. 1. Postnatal development of serine dehydratase in rat liver in vivo is blocked by actinomycin D and cycloheximide. 2. 2. Glucagon induces enzyme activity in late foetal liver in utero and stimulates postnatal development twofold, as does tryptophan injection. 3. 3. Blockade of postnatal hypoglycaemia with glucose represses enyzme synthesis by 30 per cent but is without effect on the glucagon stimulation. 4. 4. Dibutyryl 3',5'-cyclic AMP stimulates postnatal synthesis of serine dehydratase nearly twofold; the effect is completely blocked by actinomycin D. 5. 5. Dibutyryl cyclic AMP and adrenaline do not induce enzyme activity in the rat foetus.
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