Abstract
Dopamine inhibited basal, TRH-, IBMX- and A23187- stimulated prolactin secretion from rat anterior pituitary cells. However, dopamine did not inhibit prolactin secretion stimulated by elevated K + concentrations. These data are interpreted in terms of dopaminergic inhibition of both cyclic AMP production and Ca 2+ influx through agonist-, but not voltage-, dependent Ca 2+ channels.
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