Abstract

Summary The ability of the examined compounds to create ion pairs with the selected anionic dyes, allows their determination by the method of extraction spectrophotometry in the visible radiation. These ion pairs are extractable with an organic solvent immiscible with water. The procedure is based on protonisation of the studied compounds in acidic environment, and consequently their extraction in the form of associate with the anion of the acid dye into the organic phase, in this case in chloroform. Mentioned methods of analysis may be advantageously used for simple and express determination of fentanyl, alfentanil and remifentanil.

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