The possibility of calculating optimal doses in combined medicinal product (Working hypothesis)

Abstract

The purpose of the study is a theoretical justification (working hypothesis) of a possible approach to calculating doses in a combined medicinal product containing 2 pharmaceutical substances. A mathematical model is proposed, which is a multiple regression equation from two variables, which is a square polynomial. The proposed model makes it possible to calculate the optimal doses of pharmaceutical substances in a combined drug by further differentiating the regression equation in partial derivatives. Two examples of dose calculation are presented.