The polyphenols curcumin and resveratrol effectively block IL-1β and PMA-induced IL-6, IL-8 and VEGF-A expression in human rheumatoid synovial fibroblasts

B Kloesch,G Steiner,E Dietersdorfer,J Broell,H Kiener

doi:10.1136/annrheumdis-2011-201239.13

The polyphenols curcumin and resveratrol effectively block IL-1β and PMA-induced IL-6, IL-8 and VEGF-A expression in human rheumatoid synovial fibroblasts

B Kloesch, G Steiner + Show 3 more

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https://doi.org/10.1136/annrheumdis-2011-201239.13

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Journal: Annals of the Rheumatic Diseases	Publication Date: Feb 1, 2012
Citations: 1

Affiliation: Medical University of Vienna

#Synovial Fibroblasts #Human Synovial Fibroblast Cell Line + Show 8 more

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Abstract

Background and objectivesPolyphenols such as curcumin (diferuloylmethane) and resveratrol (trans-3,49,5-trihydroxystilbene) have a wide range of pharmacological and biological activities. The antioxidant, anti-inflammatory and apoptotic effects of these compounds have been...

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