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Abstract
An in vitro test for the rate of appearance of kallikrein in plasma due to contact system activation by dextran sulfate at 0 °C was applied to plasmas of 19 atopic asthma patients and 19 age- and sex-matched controls without atopy. The average prekallikrein activation rate was markedly higher in the plasmas of the atopic patients. Mean endogenous heparin levels were also elevated.
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