Abstract
abstract – In a double blind longitudinal study the plaque‐inhibiting effect of two chlorhexidine‐containing dentifrices was tested on 53 students for 2 months. The mean Plaque Index values of the groups employing active toothpastes were significantly lower than in a placebo group (p < 0.5). The differences tended to increase with time. Standardized color photographs were taken of all participants at the start and at the termination of the experiment. Brownish stains on silicate fillings and tooth surfaces were observed frequently. No damage to the oral mucosa or discoloration of the dorsum of the tongue could be detected. Storing of the dentifrices at room temperature up to 6 months caused no changes in the antibacterial activity against salivary bacteria in vitro. It is concluded that the use of a dentifrice as a vehicle for chlorhexidine might be of value in the general preventive application of the agent.
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