Abstract
Sequestration of Plasmodium-infected cells in the placenta causes significant adverse effects on mothers and their fetuses. With progress in understanding placental malaria and associated adverse consequences, this review addresses the situation in an area with high prevalence, in Blue Nile State, Sudan, where protective interventions are not adequately provided. Several studies have confirmed that malaria infection during pregnancy with parasites in the placenta, even at sub-patent level detected by molecular techniques, can result in maternal morbidity, fetal growth restriction, and reduced birth weight. Thus, malaria protection measures and antenatal care are vital for pregnant women in endemic areas. Falciparum and vivax-infected erythrocytes are able to sequester in the placenta and not easily detected in peripheral blood during antenatal period. Recently, several biological biomarkers associated with malaria infection during pregnancy were detected. Such biomarkers could be used as indicators for identifying women at risk of placental infection complications, particularly when pre-eclampsia may occur.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
