Abstract
The aim of this communication is to present an overview of the physiological basis of arterial pressure variations during positive-pressure ventilation. The review describes the effects of the mechanical breath on the right and left ventricles, and in particular the vascular waterfall effect and the reduction in venous return and the inspiratory increase in LV preload. A better understanding of the hemodynamic consequences of mechanichal ventilation will help the reader to correctly interpret arterial pressure variations and apply their derived parameters into clinical decision-making.
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