Abstract
Dysarthria is universal in Parkinson’s disease (PD) during disease progression; however, the quality of vocalization changes is often ignored. Furthermore, the role of changes in the acoustic parameters of phonation in PD patients remains unclear. We recruited 35 PD patients and 26 healthy controls to perform single, double, and multiple syllable tests. A logistic regression was performed to differentiate between protective and risk factors among the acoustic parameters. The results indicated that the mean f0, max f0, min f0, jitter, duration of speech and median intensity of speaking for the PD patients were significantly different from those of the healthy controls. These results reveal some promising indicators of dysarthric symptoms consisting of acoustic parameters, and they strengthen our understanding about the significance of changes in phonation by PD patients, which may accelerate the discovery of novel PD biomarkers.
Highlights
Dysarthria is universal in Parkinson’s disease (PD) during disease progression; the quality of vocalization changes is often ignored
Our results indicated that the jitter values were lower in PD patients than in control subjects, and there were significant differences between male participants speaking double syllables
Midi et al revealed that patients with PD had higher jitter, fundamental frequency and fundamental frequency variability than control subjects. These results indicated that the higher f0 and f0 variations in PD patients are generally attributable to the increased stiffness of the vocal folds because of the rigidity of the laryngeal musculature[7]
Summary
Dysarthria is universal in Parkinson’s disease (PD) during disease progression; the quality of vocalization changes is often ignored. The results indicated that the mean f0, max f0, min f0, jitter, duration of speech and median intensity of speaking for the PD patients were significantly different from those of the healthy controls These results reveal some promising indicators of dysarthric symptoms consisting of acoustic parameters, and they strengthen our understanding about the significance of changes in phonation by PD patients, which may accelerate the discovery of novel PD biomarkers. The speech abnormalities of patients with PD are collectively termed hypokinetic dysarthria (HKD) These speech flaws are typically characterized by increased acoustic noise, a reduced intensity of voice, harsh and breathy voice quality, increased voice nasality, monopitch, monoloudness, speech rate disturbances, the imprecise articulation of consonants, the involuntary introduction of pauses, the rapid repetitions of words and syllables and sudden deceleration or acceleration in speech. Dysphonia in PD has recently received abundant a ttention[9]
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
