Abstract
Since the announcement of the COVID-19 pandemic (March 11, 2020), the focus of the study of complications of this new coronavirus disease has been on pneumonia and acute respiratory distress syndrome. Meanwhile, with COVID-19, acute abdominal surgical diseases develop, presumably due to the tropism of the COVID-19 virus to angiotensin-converting enzyme receptors in the digestive tract. In principle, previously known coronaviruses could cause infectious peritonitis, however, such cases of coronavirus peritonitis were observed exclusively in animals. In particular, FIPV - coronavirus is the direct cause of feline infectious peritonitis. This article describes a rare, alarming case of serous fibrinous peritonitis as a casuistic manifestation of a new coronavirus infection COVID-19 directly in humans: a 55-year-old female patient. Surgical diseases that could cause the development of this peritonitis in this patient were excluded. The purpose of the article is to point out the possibility of the development of this surgical disease, as a direct complication of the new coronavirus infection COVID-19. The article also presents the author's attempt to explain in general terms the pathogenesis of the development of peritonitis in COVID-19 in humans. Observing the second year of the pandemic, extremely rare mentions in medical scientific articles of cases of primary peritonitis in COVID-19, we can conclude that this complication is not typical in this new infection. However, given the too short period since the emergence of a new coronavirus infection COVID-19 (less than two years), as well as the ability of a new strain of coronavirus to mutate, we can assume that, in principle, the possibility of developing coronavirus peritonitis in humans is not excluded in the future.
Highlights
Among the clinical manifestations of coronavirus disease COVID-19, caused by the previously unknown betacoronavirus SARS-CoV-2 [1, 2], the development of serous peritonitis is extremely rare
Looking at the available sources of information, we can say that since the proclamation of the pandemic of the new coronavirus COVID-19, only several cases of peritonitis have been reported as a direct consequence of coronavirus infection
Non-thrombotic causes described in the literature include pancreatitis, peritonitis, bloating, and colitis and are associated with tropism of the virus to angiotensin-converting enzyme (ACE) receptors in the digestive tract [7, 8]
Summary
Among the clinical manifestations of coronavirus disease COVID-19, caused by the previously unknown betacoronavirus SARS-CoV-2 [1, 2], the development of serous peritonitis is extremely rare. Mechanisms of abdominal pain in SARS-CoV-2 infection can be divided into pulmonary (with abnormalities confirmed on a computed tomography), due to the lesion lower lungs and extrapulmonary, which can be thrombotic and nonthrombotic [7, 8]. Non-thrombotic causes described in the literature include pancreatitis, peritonitis, bloating, and colitis and are associated with tropism of the virus to ACE receptors in the digestive tract [7, 8]. Is our own observation of the case of casuistic development of peritonitis in a patient with COVID-19. Gorolyuk Anna Yuriyivna: The Peritonitis as a Casuistic Clinical Manifestation of the
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