Abstract

To maintain continually renewing tissues, adult stem cells must be able to both self-renew and differentiate, and thus sit at base of homeostatic lineage hierarchies. A new paper in Development investigates the general principles regulating such lineage architectures from a theoretical perspective. To find out more about the work, we caught up with the paper's first and corresponding author Philip Greulich, Lecturer in Applied Mathematics and Theoretical Physics at the University of Southampton in the UK.

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