Abstract
During embryogenesis, cells differentiate and organise into spatially defined regions in response to varying patterns of signalling. A new paper in Development uses an optogenetic system (optoWnt) to investigate how cells organise into distinct domains in response to Wnt signalling in two-dimensional human embryonic stem cell cultures. To hear more about the story behind the paper, we caught up with the first author Nicole Repina and her PhD supervisor David Schaffer, Professor at University of California, Berkeley.
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