Abstract
Cell fate decisions are dependent on both internal and external factors, but mathematical models of this process have often neglected the external signals. A new paper in Development describes a multiscale model that integrates intracellular gene regulatory networks with a cell-cell communication network at single-cell resolution. We caught up with the authors, PhD student Megan Rommelfanger and Adam MacLean, Assistant Professor at the University of Southern California, to find out more about their research.
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