Abstract

miR-31, an evolutionarily conserved microRNA, has been studied in different contexts, such as myogenesis, skeletogenesis and cancer; however, its role in post-transcriptional regulation during development is still unclear. In a new study, Jia Song and colleagues find that miR-31 regulates local translation of cytoskeletal remodelling transcripts at the mitotic spindle to ensure proper cell division during sea urchin embryogenesis. To find out more about the story behind the paper, we caught up with first author Carolyn Remsburg and Jia Song, Associate Professor at the University of Delaware, USA.

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