Abstract
Chemokines are perhaps best known for their role in immune responses, but they can also regulate cell migration during embryonic development. A new paper in Development shows that an atypical chemokine receptor sequesters maternal CXCL12 in the placenta to prevent it from entering the embryonic bloodstream, thus ensuring proper haematopoiesis in the embryo. To learn more about the story behind the paper, we caught up with first author Ayumi Fukuoka and corresponding author Gerry Graham, the Gardiner Chair of Immunology at the University of Glasgow, UK.
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