Abstract
SUMMARY Materials from many field outbreaks of ovine toxoplasmic perinatal mortality, and also from experimental toxoplasmic infection, were examined pathologically. In the foetus there were usually multiple small foci of non-inflammatory necrosis of the central white matter of the anterior portion of the cerebral hemispheres. Less frequently there were foci of gliosis and very rarely clumps of Toxoplasma. Small chronic inflammatory foci were sometimes seen also in liver, lung and heart. In the foetal membranes there were usually multiple small foci of necrosis in the foetal cotyledons associated with hypertrophy and hyperplasia of the trophoblastic epithelium together with occasional clumps of Toxoplasma. These findings are briefly discussed and an attempt is made to trace the course of the infection.
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