Abstract
Objectives: Different pathological aspects of the aortic valve insufficiency have been revisited in order to obtain explanatory correlations. Materials and Methods: Fifteen aortic valves, surgically removed for an acquired regurgitation, have been submitted to histochemistry for elastic fibers (Weigert's stain, Van Gieson's stain, Verhoeff's stain) and mu - cins (Alcian/blue PAS stain). Results: Elastolysis, likely correlated with aging, can be considered a starting event, followed by mucoid degeneration, with a scanty remodelling attempt and a limited presence of newly formed muscle-like cells. Conclusions: The extracellular matrix degeneration, secondary to a proteolytic degradation, is supported by an enzymatic activity, related to a genetic or metabolic basic disorder.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
