Abstract
<h3>To the Editor.—</h3> The review of skin infections in the immunocompromised host in a recent issue of theArchives<sup>1</sup>omitted what is probably the most common example of that occurrence, ie, the frequent appearance of seborrheic dermatitis in patients with the acquired immunodeficiency syndrome (AIDS).<sup>2</sup>Despite the objections that have been expressed about the role of microbes in the pathogenesis of seborrheic dermatitis,<sup>3</sup>there is now over-whelming evidence in favor of microbes playing a pathogenic role,<sup>4-8</sup>and a recent reviewer has declared the argument ended.<sup>9</sup>In our own experience, AIDS-related seborrheic dermatitis is associated with large numbers of<i>Malassezia</i>organisms on affected sites and responds rapidly to treatment with 2% ketoconazole cream, thus providing further evidence of a microbial origin.<sup>10</sup>
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