Year-end Sale % OFF 
Abstract
Infection of adult mice with small doses of neuro-virulent bovine ephemeral fever virus caused a rapidly fatal encephalitis, the course of which was largely unaffected by treatment with either cyclophosphamide or anti-lymphocyte serum. Athymic mice died earlier than their thymic littermates. Mice could be protected by treatment with defective virus before infection or by passive administration of antibody if given less than 48 h after infection. Taken together these results emphasize the important protective role of antibody present at the time of infection. Viral isolation and immuno-fluorescent studies showed that the virus is confined to the central nervous system. Regular infection of suckling and adult mice by extra-cerebral routes was not possible.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
