Abstract

Advances in laboratory sciences have raised expectations of discovery of clinically useful biomarkers, but few such new tests have appeared to date. Hortin et al. (1) highlighted several challenges in the translation of promising markers into clinical laboratory tests. Translational medicine, which is currently defined as the translation of basic research into practical clinical applications, has great potential to develop and deliver new tools that may assist prevention, diagnosis, and treatment of disease (2). In the field of laboratory medicine, the transfer of promising research assays to daily laboratory practice is a challenge that may take several years and involves many sequential processes: development and validation of clinical assays, release of reagents and systems by diagnostic …

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