Abstract
Using the Warburg manometric technique, the oxygen utilization rate and the glucose oxidation rate of gingival tissue from non-diabetic and diabetic patients were compared. The oxygen utilization rate of non-diabetic tissue was significantly greater than that of the diabetic, the rates at the end of 1 hr being 0.33 ± 0.11 μl per mg tissue (wet weight) for the non-diabetic and 0.27 ± 0.14 μl per mg tissue (wet weight) for the diabetic. The glucose oxidation rate for the non-diabetic and the diabetic, as measured by the rate of formation of 14CO 2 from glucosel- 14C, was 11.45 ± 4.68 and 9.07 ± 3.18 counts/min per mg tissue (wet weight) respectively. The difference of 2.38 counts/min was significant at the 1 per cent level.
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