Abstract
1. 1. Using isotropic tracer methods, the alkaline oxidation of uric acid to oxonic acid (allantoxanic acid) and allantoxaidine has been investigated. These two compounds do not contain the imidazole ring of uric acid, as is generally believed. They are formed from carbon atoms 2, 4 and 8, and nitrogens 3 and 9 of uric acid. The third nitrogen originates 50-50 from positions 1 and 7. In addition, oxonic acid contains the former carbon 5 as a carboxyl group. 2. 2. Symmetrical triazine structures are proposed for oxonic acid, allantoxaidine, and their derivatives to replace the generally accepted imidazolidine formulas. 3. 3. An indirect method is given for the calculation of the complete N- and C-isotope distribution in labelled uric acids. It is based on isotope determinations of uric acid and simple degradation products which are easily obtained in good yield and a very pure state.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
