Abstract
AbstractEight patients are described who had a diminished functional thyroid mass after operation, radioiodine treatment or thyroiditis. All had hyperthyroid symptoms and signs, but low or normal serum protein‐bound iodine (PBI) or butanol‐extractable iodine (BEI) values. Protein‐bound radioiodine (PBI*) or conversion ratio (CR), when available, was high. The symptoms and signs subsided when thyroxin medication was employed. The condition is interpreted as a result of intense pituitary TSH stimulation of a small functioning thyroid remnant, resulting in rapid iodine and hormone turnover within a small functioning iodine space. The thyroid remnants are not able to secrete enough thyroid hormones to suppress TSH stimulation. The meaning of the hyperthyroid symptoms and signs in this form of hypothyroidism is discussed. The importance of recognition of this condition is stressed, as well as the need to consider thyroid replacement therapy after subtotal thyroidectomy, radioiodine treatment or thyroiditis.
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