The overall decrease in incidence of ovarian cancer in the United States: is this reflected in our racial ethnic groups?

Abstract

Objectives: The incidence of ovarian cancer has been decreasing in the United States. However, this decline in new cases may not be reflected in all ethnic groups. We propose to determine the racial disparities in the incidence and trends of epithelial ovarian cancers in the US. Methods: Data were extracted from the United States Cancer Statistics, 2001-2016. Trends in the incidence was analyzed by SEER*Stat 8.3.8. Chi-square test were performed for statistical analysis. Results: Of 319,257 patients with epithelial ovarian cancer, 79.9% were White, 7.8% Black, 7.9% Hispanic, 3.5% Asian, and 1.0% others. Local, regional, distant, and unknown stages represented 13.4%, 19.3%, 59.7%, and 7.7% of the study group. Serous, endometrioid, clear cell, and mucinous were found in 44.8%, 9.6%, 4.9%, and 5.8%. Overall, there was an average decrease of 2% per year in all epithelial cancers (p Conclusions: In this large population-based dataset, we found that Black and Asian patients with serous ovarian cancer have an increasing incidence. Older Black patients and those living in the Middle Atlantic, Pacific, and East North Central regions of the US also had higher incidence. Further research is warranted to elucidate preventative strategies in these high-risk groups.